Angiotropic large-cell lymphoma is a disorder characterized by an intravascular proliferation of malignant lymphoid cells. We present a patient with polyradiculoneuropathy, myelopathy, and myopathy diagnosed by peripheral nerve and muscle biopsy, who was treated and remains in stable neurologic condition.

Rev Inst Med Trop Sao Paulo. 1992 Sep-Oct;34(5):375-81.
The early diagnosis of leptospirosis by demonstrating antigens via an immunohistochemical exam of the hamstring muscle
Uip DE, Amato Neto V, Duarte MS.
Divisao de Clinica de Molestias Infecciosas e Parasitarias, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo.

Establishing an early and certain diagnosis of leptospirosis has been a difficult task. So, we analysed the histopathological alterations of the gastrocnemius muscle, and studied, for the first time, the usefulness of the immune histochemical method of peroxidase-antiperoxidase for the demonstration of the spirochete and of its products in this tissue. Histopathological observations have shown a picture of myositis, characterized by interstitial inflammatory infiltrate and necrotic-degenerative abnormalities of muscle fibers. The lesions were considered minimal in 69.45% of the patients, moderate in 19.45%, severe in 5.55% and absent in the remaining. On the other hand, the immune histochemical method identified the etiology in 94.45% what was considered very expressive.

J Genet Hum. 1987 Aug;35(4):243-9.
Value of muscle studies in the early diagnosis of Schwartz-Jampel syndrome
Vanlieferighen P, Francannet C, Dechelotte P, Malpuech G, de Laguillaumie B, Storme B.
Service de Pediatrie B et Genetique Medicale, Hotel-Dieu, Clermont-Ferrand.

The authors report a case of Schwartz-Jampel syndrome (osteo-chondro muscular dystrophy with myotonia). The diagnosis was made when the child was 3 1/2 year old. Then, there were no clinical symptoms; however, the electromyographic and histologic patterns of the disease were found. Two years later, the clinical status provided confirmation of the diagnosis. The discussion focuses on the difficulty of the diagnosis and the relevance of electrophysiological studies and muscular biopsy in order to distinguish this disease from others with similar clinical pattern (as Freeman-Sheldon, or Marden Walker syndromes).

Rinsho Shinkeigaku. 2003 May;43(5):243-8.
Nation-wide survey on muscle glycogen storage disease (MGSDs) and comparison with our experiences in diagnosis of MGSDs
Fukuda T, Sugie H, Ito M, Sugie Y, Saito K, Nishino I, Shimizu T.
Department of Pediatric Neurology, Hamamatsu City Medical Center for Developmental Medicine.

To clarify the actual frequency of each type of muscle glycogen storage diseases (MGSDs) in Japan, we performed nation-wide survey in 2001. We compared the results with our diagnostic experiences at Hamamatu City Medical Center for Developmental Medicine. The majority (approximately 80%) of the MGSDs consisted of type II, V and III in Japan. In our experiences, most of the patients were diagnosed by the assays of glycolytic enzyme activities using biopsied skeletal muscles. However, the biochemical diagnoses of MGSDs type II, III, IV, and IX can be made using blood samples. Additionally, common genetic mutation (708/709 delTTC) of myophosphorylase gene has been found approximately in 50% of the Japanese patients with MGSDs type V. Therefore, approximately 70% of the MGSDs may be diagnosed by biochemical and genetic analysis using blood samples. Additional survey on McArdle's disease showed that the onset of muscle symptoms in McArdle's disease were variable, however, fixed muscular symptoms such as muscle weakness and muscle atrophy were present in 45% of patients.